Science is not a heartless pursuit of objective information; it is a creative human activity.

Skepticism is the agent of reason against organized irrationalism–and is therefore one of the keys to human social and civic decency.

My potential salvation…must remain an unswerving commitment to treat generality only as it emerges from little things that arrest us and open our eyes with aha — while direct, abstract, learned assaults upon generalities usually glaze them over.

We have become, by the power of a glorious evolutionary accident called intelligence, the stewards of life’s continuity on earth. We did not ask for this role, but we cannot abjure it. We may not be suited to it, but here we are.

In science, ‘fact’ can only mean ‘confirmed to such a degree that it would be perverse to withhold provisional assent.’ I suppose that apples might start to rise tomorrow, but the possibility does not merit equal time in physics classrooms.

Science is an integral part of culture. It’s not this foreign thing, done by an arcane priesthood. It’s one of the glories of the human intellectual tradition.

Scientists have power by virtue of the respect commanded by the discipline… We live with poets and politicians, preachers and philosophers. All have their ways of knowing, and all are valid in their proper domain. The world is too complex and interesting for one way to hold all the answers.

Few tragedies can be more extensive than the stunting of life, few injustices deeper than the denial of an opportunity to strive or even to hope, by a limit imposed from without, but falsely identified as lying within.

Goethe died in 1832. As you know, Goethe was very active in science. In fact, he did some very good scientific work in plant morphology and mineralogy. But he was quite bitter at the way in which many scientists refused to grant him a hearing because he was a poet and therefore, they felt, he couldn’t be serious.

We are here because one odd group of fishes had a peculiar fin anatomy that could transform into legs for terrestrial creatures; because the earth never froze entirely during an ice age; because a small and tenuous species, arising in Africa a quarter of a million years ago, has managed, so far, to survive by hook and by crook. We may yearn for a ‘higher answer’– but none exists

I had learned that a dexterous, opposable thumb stood among the hallmarks of human success. We had maintained, even exaggerated, this important flexibility of our primate forebears, while most mammals had sacrificed it in specializing their digits. Carnivores run, stab, and scratch. My cat may manipulate me psychologically, but he’ll never type or play the piano.

The human mind delights in finding pattern—so much so that we often mistake coincidence or forced analogy for profound meaning. No other habit of thought lies so deeply within the soul of a small creature trying to make sense of a complex world not constructed for it.